Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.36 |
| ▸ | MME | P08473 | 2/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 3/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.31 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891923 | 0.85 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2LAP3ANPEP | |
| Leucine SCHEMBL891924 | 0.76 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2LAP3RNPEP | |
| Leucine SCHEMBL891921 | 0.76 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2LAP3RNPEP | |
| SCHEMBL288383 | 0.76 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL18050156 | 0.76 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6038226 | 0.76 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| Threonine SCHEMBL4493263 | 0.76 | PTGS1 (0.42) | SLC7A5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL20898389 | 0.75 | SLC7A5 (0.55) | SLC7A5SLC1A3SLC1A2LAP3ANPEP | |
| Leucine SCHEMBL15323703 | 0.74 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2LAP3RNPEP | |
| Leucine SCHEMBL15323699 | 0.74 | SLC7A5 (0.72) | SLC7A5SLC1A3SLC1A2LAP3RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836832-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155458-A1 | EARLY TRIMESTER SCREENING FOR EARLY- AND LATE-ONSET PREECLAMPSIA | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |