Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.42 |
| ▸ | ENPEP | Q07075 | 4/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | P2RY10 | O00398 | 2/20 | 0.31 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.31 |
| ▸ | CASR | P41180 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497690 | 0.93 | PTGS1 (0.48) | PTGS1SLC7A11ENPEPSLC7A5SLC1A3 | |
| SCHEMBL2702062 | 0.82 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2SLC1A1P2RY10 | |
| Threonine SCHEMBL16982372 | 0.81 | SLC7A5 (0.41) | SLC7A5SLC1A3SLC1A2SLC1A1P2RY10 | |
| SCHEMBL18050156 | 0.81 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1P2RY10 | |
| SCHEMBL6038226 | 0.81 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1P2RY10 | |
| SCHEMBL288383 | 0.81 | SLC7A5 (0.44) | SLC7A5SLC1A3SLC1A2SLC1A1P2RY10 | |
| Threonine SCHEMBL4493265 | 0.81 | PTGS1 (0.67) | PTGS1SLC7A11ENPEPSLC7A5SLC1A3 | |
| Threonine SCHEMBL971052 | 0.81 | PTGS1 (0.67) | PTGS1SLC7A11ENPEPSLC7A5SLC1A3 | |
| Threonine SCHEMBL971053 | 0.81 | PTGS1 (0.67) | PTGS1SLC7A11ENPEPSLC7A5SLC1A3 | |
| Threonine SCHEMBL27769582 | 0.81 | PTGS1 (0.67) | PTGS1SLC7A11ENPEPSLC7A5SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592188-B2 | environmentally sensitive fluorescent dye covalently linked to a binding domain which has specific affinity for a target molecule; fluorescence resonance energy transfer; detecting changes in the binding, conformational change; detecting human immunodeficiency virus | THE SCRIPPS RESEARCH INSTITUTE (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1735453-A2 | FLUORESCENT SIGNAL EMITTING LIVE CELL BIOSENSOR MOLECULES AND DYES FOR DETECTION AND QUANTIFICATION OF PROTEIN ACTIVITIES | The Scripps Research Institute (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20060029946-A1 | Live cell biosensors | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2006-02-09 | — | — | US | disclosed |
| WO-2005088308-A2 | FLUORESCENT SIGNAL EMITTING LIVE CELL BIOSENSOR MOLECULES AND DYES FOR DETECTION AND QUANTIFICATION OF PROTEIN ACTIVITIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 2005-09-22 | — | — | WO | disclosed |