Cysteine

Cysteine

SCHEMBL1532397

N[C@@H](CS)C(=O)O.[Cl-].[H+]

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Cysteine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cysteine SCHEMBL3922894 1.00
Cysteine SCHEMBL3697868 0.97
Cysteine SCHEMBL11873934 0.94
Cysteine SCHEMBL27709352 0.94
Cysteine SCHEMBL27709351 0.94
Cysteine SCHEMBL28854295 0.94 PTGS1 (0.89)
Cysteine SCHEMBL7898895 0.94 PTGS1 (1.00)
Cysteine SCHEMBL95110 0.94
Cysteine SCHEMBL339562 0.94 PTGS1 (1.00)
Cysteine SCHEMBL21110883 0.94 PTGS1 (1.00)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102359-A1 COMBINATION TREATMENT OF DERMAL AND TRANSDERMAL FIBROTIC DISEASES, DISORDERS AND ASSOCIATED PAIN AND INFLAMMATION ERESINA LLC (US) 2026-04-16 US disclosed
US-20250195439-A1 METHOD FOR TREATING LOCAL LESION DISEASE CHENGDU KUACHANGAOPU MEDICAL TECHNOLOGY CO., LTD. (CN) 2025-06-19 US disclosed
EP-3845247-B1 USE OF AMINO ACID BASED NUTRIENTS AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME CHENGDU KUACHANGAOPU MEDICAL TECH CO LTD (CN) 2025-06-04 EP disclosed
CN-115398236-B Method for the electrophoretic deglycosylation of glycosylated proteins 瑞泽恩制药公司 2024-06-11 CN disclosed
US-11968998-B2 L-cysteine-treated proteins with altered functionalities and preparations thereof MGPI PROCESSING, INC. (US) 2024-04-30 US disclosed
EP-4354145-A2 DEGLYCOSYLATION METHODS FOR ELECTROPHORESIS OF GLYCOSYLATED PROTEINS Regeneron Pharmaceuticals, Inc. (US) 2024-04-17 EP disclosed
CN-117887613-A Bifidobacterium longum subspecies infantis capable of relieving autism spectrum disorder and application thereof 深圳未知君生物科技有限公司 2024-04-16 CN disclosed
CN-117871866-A System and method for characterizing protein dimerization 瑞泽恩制药公司 2024-04-12 CN disclosed
EP-4348234-A1 MICROPCHIP CAPILLARY ELECTROPHORESIS ASSAYS AND REAGENTS Regeneron Pharmaceuticals, Inc. (US) 2024-04-10 EP disclosed
EP-4085253-B1 DEGLYCOSYLATION METHODS FOR ELECTROPHORESIS OF GLYCOSYLATED PROTEINS REGENERON PHARMA (US) 2024-03-13 EP disclosed
EP-2292585-A1 Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound APTUIT (KANSAS CITY), LLC (US) 2011-03-09 EP disclosed
US-20090281195-A1 NOVEL COCRYSTALLIZATION S.S.C.I., INC. (US) 2009-11-12 US disclosed
US-7452555-B2 Cocrystallization S.S.C.I., INC. (US) 2008-11-18 US disclosed
US-20070287194-A1 Screening For Solid Forms By Ultrasound Crystallization And Cocrystallization Using Ultrasound S.S.C.I., INC 2007-12-13 US disclosed
US-20070088508-A1 Cocrystallization methods APTUIT (WEST LAFAYETTE), LLC 2007-04-19 US disclosed
EP-1265612-B1 PHARMACEUTICAL COMPOSITION COMPRISING PEMETREXED TOGETHER WITH MONOTHIOGLYCEROL, L-CYSTEIN OR THIOGLYCOLIC ACID LILLY CO ELI (US) 2004-05-26 EP disclosed
US-6686365-B2 Pharmaceutical composition ELI LILLY AND COMPANY 2004-02-03 US disclosed
US-20030212083-A1 PHARMACEUTICAL COMPOSITION LILLY FORSCHUNG GMBH (DE) 2003-11-13 US disclosed
EP-1265612-A1 PHARMACEUTICAL COMPOSITION COMPRISING PEMETREXED TOGETHER WITH MONOTHIOGLYCEROL, L-CYSTEIN OR THIOGLYCOLIC ACID ELI LILLY AND COMPANY (US) 2002-12-18 EP disclosed
WO-2001056575-A1 PHARMACEUTICAL COMPOSITION COMPRISING PEMETREXED TOGETHER WITH MONOTHIOGLYCEROL L-CYSTEIN OR THIOGLYCOLIC ACID ELI LILLY AND COMPANY (US) 2001-08-09 WO disclosed