Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Cysteine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cysteine SCHEMBL27709351 | 1.00 | — | — | |
| Cysteine SCHEMBL652294 | 0.94 | PTGS1 (0.89) | — | |
| Cysteine SCHEMBL652295 | 0.94 | — | — | |
| Cysteine SCHEMBL10935452 | 0.94 | — | — | |
| Cysteine SCHEMBL16685304 | 0.94 | — | — | |
| Cysteine SCHEMBL3922894 | 0.94 | — | — | |
| Cysteine SCHEMBL1532397 | 0.94 | — | — | |
| Cysteine SCHEMBL28854295 | 0.94 | PTGS1 (0.89) | — | |
| Cysteine SCHEMBL4289403 | 0.94 | — | — | |
| Cysteine SCHEMBL21110883 | 0.94 | PTGS1 (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105748310-B | A kind of synergist and its preparation and application | 中国中化股份有限公司 | 2018-08-24 | — | — | CN | claimed |
| CN-105748310-A | Synergist, and preparation method and application thereof | 中国中化股份有限公司 | 2016-07-13 | — | — | CN | claimed |
| CN-105748310-B | A kind of synergist and its preparation and application | 中国中化股份有限公司 | 2018-08-24 | — | — | CN | disclosed |
| CN-105748310-A | Synergist, and preparation method and application thereof | 中国中化股份有限公司 | 2016-07-13 | — | — | CN | disclosed |
| CN-101303363-B | Multipurpose micro-flow liquid comprehensive processing system | TIANJIN XIANSHI OPTICS TECHNOLOGY CO LTD | 2012-11-21 | — | — | CN | disclosed |
| CN-101303363-A | Multipurpose micro-flow liquid comprehensive processing system | TIANJIN XIANSHI OPTICS TECHNOL (CN) | 2008-11-12 | — | — | CN | disclosed |
| CN-101234193-A | Stable water solution containing recombination human serum albumin fusion interferon | SINOBIO BIOTECH CO (CN) | 2008-08-06 | — | — | CN | disclosed |