Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 20/20 | 0.51 |
| ▸ | FPR3 | P25089 | 14/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2681902 | 0.85 | FPR2 (0.52) | FPR2FPR3 | |
| SCHEMBL855173 | 0.75 | FPR2 (0.60) | FPR2FPR3 | |
| SCHEMBL2683106 | 0.67 | FPR2 (1.00) | FPR2FPR3 | |
| SCHEMBL15323522 | 0.65 | FPR2 (0.50) | FPR2FPR3 | |
| SCHEMBL15324461 | 0.64 | FPR2 (0.51) | FPR2FPR3 | |
| SCHEMBL856243 | 0.64 | FPR2 (0.57) | FPR2FPR3 | |
| SCHEMBL855932 | 0.63 | FPR2 (0.74) | FPR2FPR3 | |
| SCHEMBL2683253 | 0.63 | FPR2 (0.74) | FPR2FPR3 | |
| SCHEMBL2683068 | 0.62 | FPR2 (1.00) | FPR2FPR3 | |
| SCHEMBL856317 | 0.62 | FPR2 (0.51) | FPR2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563714-B2 | Bridged spiro [2.4] heptane derivatives as ALX receptor and/or FPRL2 agonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-10-22 | — | — | US | claimed |