Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380963 | 0.82 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL29291217 | 0.81 | MGAM (0.34) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL1100419 | 0.77 | — | — | |
| SCHEMBL3367785 | 0.74 | EPHX2 (0.32) | — | |
| SCHEMBL11908661 | 0.74 | — | — | |
| SCHEMBL11837638 | 0.74 | ALDH1A1 (0.39) | MGAMGAASIMGAM2GLO1 | |
| SCHEMBL28783646 | 0.73 | MGAM (0.41) | MGAMGAASIMGAM2GLO1 | |
| SCHEMBL12516495 | 0.73 | MMP1 (0.44) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL8682690 | 0.72 | CHRM1 (0.36) | — | |
| SCHEMBL6685614 | 0.71 | ALDH1A1 (0.50) | MGAMGAASIMGAM2GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2836833-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | Wayne State University (US) | 2015-02-18 | — | — | EP | disclosed |
| WO-2013155456-A1 | PRENATAL SCREENING FOR DOWN SYNDROME AND TRISOMY 18 | WAYNE STATE UNIVERSITY (US) | 2013-10-17 | — | — | WO | disclosed |