Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420531 | 1.00 | KDM4E (0.48) | KDM4ELMNAHTTKMT2AALDH1A1 | |
| SCHEMBL30538681 | 1.00 | KDM4E (0.48) | KDM4ELMNAHTTKMT2AALDH1A1 | |
| SCHEMBL13950213 | 1.00 | KDM4E (0.48) | KDM4ELMNAHTTKMT2AALDH1A1 | |
| SCHEMBL12297882 | 0.80 | FAAH (0.54) | LMNAHTTKMT2AALDH1A1RAB9A | |
| SCHEMBL5736711 | 0.61 | KDM4E (0.45) | KDM4EKMT2AALDH1A1RAB9ARECQL | |
| SCHEMBL5736714 | 0.61 | KDM4E (0.45) | KDM4EKMT2AALDH1A1RAB9ARECQL | |
| SCHEMBL608814 | 0.59 | ABL1 (0.68) | KDM4EKMT2AALDH1A1RAB9ARECQL | |
| SCHEMBL5737133 | 0.59 | KDM4E (0.43) | KDM4EHTTKMT2AALDH1A1RAB9A | |
| SCHEMBL5737136 | 0.59 | KDM4E (0.43) | KDM4EHTTKMT2AALDH1A1RAB9A | |
| SCHEMBL10662771 | 0.58 | FAAH (0.54) | KMT2AALDH1A1S1PR1S1PR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8563511-B2 | Treatment of pulmonary hypertension using an agent that inhibits a tissue factor pathway | UNIVERSITY OF ROCHESTER (US) | 2013-10-22 | — | — | US | disclosed |