Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13950213 | 0.80 | KDM4E (0.48) | FAAHLMNATSHRHTTMEN1 | |
| SCHEMBL15324324 | 0.80 | KDM4E (0.48) | FAAHLMNATSHRHTTMEN1 | |
| SCHEMBL10667719 | 0.78 | FAAH (0.71) | FAAHMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10667710 | 0.78 | FAAH (0.71) | FAAHMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10668048 | 0.76 | FAAH (0.56) | FAAHLMNAMEN1KMT2AMAPT | |
| SCHEMBL10666307 | 0.74 | AURKA (0.58) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL10666312 | 0.74 | AURKA (0.58) | LMNAMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL3887237 | 0.73 | FAAH (0.80) | FAAHLMNAMEN1KMT2AMAPT | |
| SCHEMBL3887240 | 0.73 | FAAH (0.80) | FAAHLMNAMEN1KMT2AMAPT | |
| SCHEMBL17295253 | 0.72 | MEN1 (0.67) | FAAHLMNAMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8906937-B2 | Flavivirus inhibitors and methods of their use | GEORGETOWN UNIVERSITY (US) | 2014-12-09 | — | — | US | disclosed |
| US-8906937-B2 | Flavivirus inhibitors and methods of their use | GEORGETOWN UNIVERSITY (US) | 2014-12-09 | — | — | US | disclosed |
| US-20140038962-A1 | Flavivirus Inhibitors and Methods of Their Use | GEORGETOWN UNIVERSITY (US) | 2014-02-06 | — | — | US | disclosed |
| US-20140038962-A1 | Flavivirus Inhibitors and Methods of Their Use | GEORGETOWN UNIVERSITY (US) | 2014-02-06 | — | — | US | disclosed |
| US-8563580-B2 | Flavivirus inhibitors and methods for their use | GEORGETOWN UNIVERSITY (US) | 2013-10-22 | — | — | US | disclosed |
| US-8563580-B2 | Flavivirus inhibitors and methods for their use | GEORGETOWN UNIVERSITY (US) | 2013-10-22 | — | — | US | disclosed |
| US-20110224207-A1 | FLAVIVIRUS INHIBITORS AND METHODS FOR THEIR USE | GEORGETOWN UNIVERSITY (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224207-A1 | FLAVIVIRUS INHIBITORS AND METHODS FOR THEIR USE | GEORGETOWN UNIVERSITY (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010039538-A2 | FLAVIVIRUS INHIBITORS AND METHODS FOR THEIR USE | GEORGETOWN UNIVERSITY (US) | 2010-04-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224207-A1 | FLAVIVIRUS INHIBITORS AND METHODS FOR THEIR USE | SERPINB1, SPINT2, MME | FAAH 558/4885LMNA 2214/4885TSHR 4596/4885 |
| US-20140038962-A1 | Flavivirus Inhibitors and Methods of Their Use | SERPINB1, SPINT2, MME | FAAH 656/4885LMNA 2268/4885TSHR 4631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.