SCHEMBL1532487

SCHEMBL1532487

O=C(O)CCc1ccc(OCCCCCCO)cc1

nearest known ligand 0.72

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.72
LMNA P02545 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
FFAR4 Q5NUL3 3/20 0.58
ITGB3 P05106 1/20 0.58
ITGA2B P08514 1/20 0.58
S1PR1 P21453 4/20 0.57
S1PR3 Q99500 2/20 0.57
S1PR5 Q9H228 1/20 0.57
PPARG P37231 2/20 0.56
PPARD Q03181 1/20 0.56
PPARA Q07869 1/20 0.56
S1PR4 O95977 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4530820 0.87 FFAR1 (0.88) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL4656572 0.86 FFAR1 (0.97) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL6497674 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL2183912 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL17320238 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL3488457 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL8378949 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL8558255 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL2185137 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1
SCHEMBL6496565 0.86 LMNA (0.79) FFAR1LMNAL3MBTL1FFAR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE42221-E1 Polymerizable liquid crystal composition and polymer thereof CHISSO CORPORATION (JP) 2011-03-15 US disclosed
US-7393569-B2 Hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyl acrylates); hexafluoroisopropylidenebis- and sulfonylbis-(phenoxycarbonylphenoxyalkyloxetanes; stabilizes polymerizable liquid crystal compositions for a long time and controls the alignment of liquid crystal molecules CHISSO CORPORATION (JP) 2008-07-01 US disclosed
US-7378135-B2 Polymerizable liquid crystal composition and optically anisotropic thin film CHISSO CORPORATION (JP) 2008-05-27 US disclosed
US-20060278851-A1 Polymerizable liquid crystal composition and polymer thereof CHISSO CORPORATION AND CHISSO PETROCHEMICAL CORPORATION 2006-12-14 US disclosed
US-20060222784-A1 Polymerizable liquid crystal composition and optically anisotropic thin film JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060278851-A1 Polymerizable liquid crystal composition and polymer thereof NCAPD2, LANCL2, TAF1 FFAR1 659/4885LMNA 2785/4885L3MBTL1 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.