SCHEMBL6496565

SCHEMBL6496565

CCCCCCCCCCCCOc1ccc(CCC(=O)O)cc1

nearest known ligand 0.79

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.79
L3MBTL1 Q9Y468 1/20 0.79
FFAR1 O14842 4/20 0.70
S1PR4 O95977 2/20 0.70
S1PR1 P21453 2/20 0.70
S1PR3 Q99500 2/20 0.70
PLA2G4B P0C869 7/20 0.65
S1PR5 Q9H228 1/20 0.64
TP53 P04637 1/20 0.62
TSHR P16473 1/20 0.62
FFAR4 Q5NUL3 1/20 0.59
THRA P10827 1/20 0.59
THRB P10828 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3488457 1.00 LMNA (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1
SCHEMBL17320238 1.00 LMNA (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1
SCHEMBL2183912 1.00 LMNA (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1
SCHEMBL2185137 1.00 LMNA (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1
SCHEMBL6497674 1.00 LMNA (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1
SCHEMBL8558255 1.00 LMNA (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1
SCHEMBL8378949 1.00 LMNA (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1
Hydrochloric Acid SCHEMBL10803998 0.98 LMNA (0.77) LMNAL3MBTL1FFAR1S1PR4S1PR1
SCHEMBL24723561 0.98 L3MBTL1 (0.82) LMNAL3MBTL1FFAR1S1PR4S1PR1
Hydrochloric Acid SCHEMBL10807470 0.97 L3MBTL1 (0.79) LMNAL3MBTL1FFAR1S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050222423-A1 Carboxylic acid derivative TAISHO PHARMECEUTICAL CO., LTD. (JP) 2005-10-06 US disclosed
EP-1466891-A1 CARBOXYLIC ACID DERIVATIVE TAISHO PHARMACEUTICAL CO., LTD (JP) 2004-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050222423-A1 Carboxylic acid derivative KDR, FLT1, FLT4 LMNA 4447/4885L3MBTL1 3879/4885FFAR1 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.