SCHEMBL15324915

SCHEMBL15324915

CC(=O)Oc1ccc(/C=C/C(=O)OCCCO)cc1OC(C)=O

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 11/20 0.73
APP P05067 4/20 0.56
JUN P05412 1/20 0.54
NFKB1 P19838 1/20 0.54
KDM4E B2RXH2 1/20 0.51
JAK2 O60674 1/20 0.51
ALDH1A1 P00352 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MET P08581 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24617861 0.91 ALOX5 (0.74) ALOX5APPJUNNFKB1KDM4E
SCHEMBL8034404 0.91 ALOX5 (0.79) ALOX5JUNNFKB1KDM4EJAK2
SCHEMBL28181780 0.86 ALOX5 (0.72) ALOX5JUNNFKB1KDM4EJAK2
SCHEMBL15384911 0.84 ALOX5 (0.66) ALOX5APPNFKB1KDM4EALDH1A1
SCHEMBL29120857 0.82 ALOX5 (0.68) ALOX5APPJUNNFKB1
SCHEMBL13498777 0.81 ALOX5 (0.68) ALOX5JUNNFKB1KDM4EJAK2
SCHEMBL15378926 0.81 TTR (0.74) ALOX5APPNFKB1KDM4EALDH1A1
SCHEMBL8031865 0.81 ALOX5 (0.68) ALOX5JUNNFKB1KDM4EJAK2
SCHEMBL2602745 0.81 TTR (0.74) ALOX5APPNFKB1KDM4EALDH1A1
SCHEMBL13997727 0.81 ALOX5 (0.56) ALOX5JUNNFKB1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841066-B1 ANTI-INFLUENZA AGENT CONJUGATED TO ANTI-INFLAMMATORY AGENT ACADEMIA SINICA (TW) 2021-02-17 EP disclosed
EP-3524272-A1 ENHANCED ANTI-INFLUENZA AGENTS CONJUGATED WITH ANTI-INFLAMMATORY ACTIVITY Academia Sinica (TW) 2019-08-14 EP disclosed
US-20130274229-A1 ENHANCED ANTI-INFLUENZA AGENTS CONJUGATED WITH ANTI-INFLAMMATORY ACTIVITY ACADEMIA SINICA (TW) 2013-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130274229-A1 ENHANCED ANTI-INFLUENZA AGENTS CONJUGATED WITH ANTI-INFLAMMATORY ACTIVITY NEU1, CTSA, CA7 ALOX5 229/4885APP 4018/4885JUN 1158/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.