Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16583755 | 0.91 | BCHE (0.46) | MTNR1AMTNR1BKMT2ACNR2GAA | |
| Hydrochloric Acid SCHEMBL16583753 | 0.90 | BCHE (0.45) | MTNR1AMTNR1BKMT2ACNR2GAA | |
| SCHEMBL15325667 | 0.82 | MTNR1A (0.51) | MTNR1AMTNR1BCNR2MAPTEGLN3 | |
| SCHEMBL15323905 | 0.81 | BCHE (0.47) | KMT2ACNR2GAAHPGDEGLN3 | |
| Hydrochloric Acid SCHEMBL16583804 | 0.77 | BCHE (0.44) | MTNR1AMTNR1BKMT2ACNR2GAA | |
| SCHEMBL3044408 | 0.75 | EGLN3 (0.68) | GAAHPGDMAPTRAB9AEGLN3 | |
| SCHEMBL28306951 | 0.74 | PKM (0.59) | KMT2AGAAHPGDMAPTMEN1 | |
| SCHEMBL30458035 | 0.74 | PKM (0.59) | KMT2AGAAHPGDMAPTMEN1 | |
| SCHEMBL27968564 | 0.74 | MAPT (0.66) | KMT2AMAPTRAB9AMEN1SMN1; SMN2 | |
| SCHEMBL11343677 | 0.73 | MAPT (0.48) | MTNR1AMTNR1BKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013150529-A2 | INDOLE, INDOLINE DERIVATIVES, COMPOSITIONS COMPRISING THEM AND USES THEREOF | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) | 2013-10-10 | — | — | WO | disclosed |