Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15326626 | 0.96 | ALDH1A1 (0.45) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL16087862 | 0.88 | LMNA (0.43) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL15326527 | 0.87 | KDM4E (0.44) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL15326528 | 0.86 | LMNA (0.41) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL15326526 | 0.84 | LMNA (0.42) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL15326553 | 0.82 | HDAC4 (0.46) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL16034867 | 0.77 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL29848625 | 0.76 | ALDH1A1 (0.68) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL15324846 | 0.76 | ALDH1A1 (0.68) | ALDH1A1LMNAKDM4ETDP1NPC1 | |
| SCHEMBL15326558 | 0.76 | NPC1 (0.49) | ALDH1A1LMNAKDM4ETDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975288-B2 | F2 derivatives as antibacterial agents | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-03-10 | — | — | US | disclosed |
| US-8975288-B2 | F2 derivatives as antibacterial agents | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-03-10 | — | — | US | disclosed |
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION | 2014-09-18 | — | — | US | disclosed |
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION | 2014-09-18 | — | — | US | disclosed |
| WO-2013154793-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | NR2C2, H1-10, NR2F2 | ALDH1A1 3673/4885LMNA 4547/4885KDM4E 3660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.