Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL153191 | 0.79 | ALDH1A1 (0.83) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL12492183 | 0.79 | ALDH1A1 (1.00) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29848625 | 0.77 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15324846 | 0.77 | ALDH1A1 (0.68) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15323648 | 0.75 | KDM4E (0.73) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL31001629 | 0.75 | CYP2C19 (0.73) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15210657 | 0.74 | CYP1A2 (0.72) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18932461 | 0.74 | CYP1A2 (0.66) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15326621 | 0.73 | KDM4E (0.69) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11442601 | 0.70 | KDM4E (0.51) | ALDH1A1HPGDCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8975288-B2 | F2 derivatives as antibacterial agents | THE PENN STATE RESEARCH FOUNDATION (US) | 2015-03-10 | — | — | US | disclosed |
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION | 2014-09-18 | — | — | US | disclosed |
| WO-2013154793-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275192-A1 | F2 DERIVATIVES AS ANTIBACTERIAL AGENTS | NR2C2, H1-10, NR2F2 | ALDH1A1 3673/4885HPGD 3401/4885CYP1A2 492/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.