Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | RAB9A | P51151 | 4/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15210526 | 0.86 | ALDH1A1 (0.65) | RAB9AALDH1A1MAPTKMT2ANPC1 | |
| SCHEMBL153191 | 0.85 | ALDH1A1 (0.83) | CYP1A2CYP2C9HPGDCYP2C19RAB9A | |
| SCHEMBL31001629 | 0.82 | CYP2C19 (0.73) | CYP1A2CYP2C9HPGDCYP2C19RAB9A | |
| SCHEMBL12492183 | 0.78 | ALDH1A1 (1.00) | CYP1A2CYP2C9HPGDCYP2C19RAB9A | |
| SCHEMBL15326531 | 0.74 | ALDH1A1 (0.65) | CYP1A2CYP2C9HPGDCYP2C19RAB9A | |
| SCHEMBL3099561 | 0.72 | RAB9A (0.62) | HPGDRAB9AALDH1A1HTTMAPT | |
| SCHEMBL29848625 | 0.71 | ALDH1A1 (0.68) | CYP1A2CYP2C9HPGDCYP2C19RAB9A | |
| SCHEMBL25394310 | 0.70 | MAPT (0.71) | CYP1A2CYP2C9CYP2C19RAB9AALDH1A1 | |
| SCHEMBL28044831 | 0.70 | MAPT (0.84) | CYP1A2CYP2C9CYP2C19RAB9AALDH1A1 | |
| SCHEMBL7566341 | 0.70 | MAPT (0.66) | HPGDRAB9AALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150031537-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | claimed |
| EP-2817298-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | claimed |
| WO-2013124245-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | claimed |
| US-9169219-B2 | Herbicidally active 4-nitro-substituted N-(tetrazol-5-yl)-, N-(triazol-5-yl)-, and N-(1,3,4-0XADIAZOL-2-yl)aryl carboxylic acid amides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-20150031537-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-01-29 | — | — | US | disclosed |
| EP-2817298-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124245-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150031537-A1 | HERBICIDALLY ACTIVE 4-NITRO-SUBSTITUTED N-(TETRAZOL-5-YL)-, N-(TRIAZOL-5-YL)-, AND N-(1,3,4-OXADIAZOL-2-YL)ARYL CARBOXYLIC ACID AMIDES | AADAC, NAT1, AOX1 | CYP1A2 65/4885CYP2C9 101/4885HPGD 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.