Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15326742 | 0.83 | MAPT (0.43) | ALDH1A1MAPTKDM4ELMNARAB9A | |
| SCHEMBL15326674 | 0.81 | ALDH1A1 (0.40) | ALDH1A1MAPTKDM4EHPGDTDP1 | |
| SCHEMBL3360701 | 0.74 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ETPMTNPC1 | |
| SCHEMBL15326675 | 0.71 | ALDH1A1 (0.39) | ALDH1A1MAPTKDM4EHPGDMEN1 | |
| SCHEMBL1705814 | 0.71 | ALDH1A1 (0.62) | ALDH1A1MAPTKDM4ENPC1LMNA | |
| SCHEMBL15326769 | 0.70 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EPDE4BHPGD | |
| SCHEMBL27971530 | 0.69 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EPDE4BHPGD | |
| SCHEMBL14991099 | 0.69 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL9362618 | 0.68 | TPMT (0.46) | ALDH1A1MAPTTPMTSMN1; SMN2TDP1 | |
| SCHEMBL5767809 | 0.67 | TSHR (0.47) | ALDH1A1MAPTNPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013152683-A1 | BICYCLE SUBSTITUTED PYRAZOLONEAZO DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 齐鲁制药有限公司 (CN) | 2013-10-17 | — | — | WO | disclosed |