Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27971530 | 0.99 | ALDH1A1 (0.41) | ALDH1A1MAPTKDM4EHPGDTDP1 | |
| SCHEMBL15326689 | 0.87 | MAPT (0.40) | ALDH1A1MAPTKDM4EHPGDTDP1 | |
| SCHEMBL27971529 | 0.85 | MAPT (0.40) | ALDH1A1MAPTKDM4EHPGDTDP1 | |
| SCHEMBL27940470 | 0.76 | DHODH (0.44) | MAPTHPGDTDP1POLBRXRA | |
| SCHEMBL27971678 | 0.75 | MAOB (0.35) | MAPTTDP1POLBRXRARXRB | |
| SCHEMBL27921796 | 0.74 | MAOA (0.36) | POLBRXRARXRB | |
| SCHEMBL15326750 | 0.74 | MAOB (0.36) | MAPTTDP1POLBRXRARXRB | |
| SCHEMBL27921772 | 0.70 | HPD (0.33) | MAPTTDP1RXRARXRB | |
| SCHEMBL15326673 | 0.70 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EHPGDTDP1 | |
| SCHEMBL629645 | 0.69 | POLB (0.42) | MAPTTDP1POLBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013152683-A1 | BICYCLE SUBSTITUTED PYRAZOLONEAZO DERIVATIVES AND PREPARATION METHOD AND USE THEREOF | 齐鲁制药有限公司 (CN) | 2013-10-17 | — | — | WO | disclosed |