SCHEMBL1532676

SCHEMBL1532676

O=c1n(CCOCCO)c(=O)n(CCOCCO)c(=O)n1CCOCCO

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
TSHR P16473 2/20 0.48
MAPK1 P28482 1/20 0.48
MGLL Q99685 1/20 0.37
ALDH1A1 P00352 1/20 0.35
NSD2 O96028 1/20 0.33
PABPC1 P11940 1/20 0.33
CASP6 P55212 1/20 0.33
PAX8 Q06710 1/20 0.33
HTR1A P08908 1/20 0.33
PNP P00491 1/20 0.33
P2RX3 P56373 1/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL837375 0.92 MEN1 (0.43) MEN1KMT2ATSHRMAPK1MGLL
SCHEMBL12123148 0.91 KMT2A (0.40) MEN1KMT2ATSHRMAPK1MGLL
SCHEMBL12123151 0.91 KMT2A (0.40) MEN1KMT2ATSHRMAPK1MGLL
SCHEMBL837378 0.88 MEN1 (0.45) MEN1KMT2ATSHRMAPK1MGLL
SCHEMBL838042 0.88 MEN1 (0.45) MEN1KMT2ATSHRMAPK1MGLL
SCHEMBL837376 0.88 MEN1 (0.45) MEN1KMT2ATSHRMAPK1MGLL
SCHEMBL13413749 0.84 MEN1 (0.38) MEN1KMT2ATSHRMAPK1SMN1; SMN2
SCHEMBL13413750 0.84 MEN1 (0.38) MEN1KMT2ATSHRMAPK1SMN1; SMN2
SCHEMBL13133746 0.79 ALDH1A1 (0.44) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL14790957 0.77 ALDH1A1 (0.58) MEN1KMT2ATSHRMAPK1MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2470331-B1 STRUCTURED ABRASIVE ARTICLE AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES CO (US) 2018-09-19 EP disclosed
US-9482955-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2016-11-01 US disclosed
US-20140080054-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PLATE MAKING METHOD THEREOF FUJIFILM CORPORATION (JP) 2014-03-20 US disclosed
US-8425278-B2 Structured abrasive article and method of using the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-23 US disclosed
EP-2470331-A2 STRUCTURED ABRASIVE ARTICLE AND METHOD OF USING THE SAME 3M Innovative Properties Company (US) 2012-07-04 EP disclosed
WO-2011028556-A2 STRUCTURED ABRASIVE ARTICLE AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY (US) 2011-03-10 WO disclosed
US-20110053460-A1 STRUCTURED ABRASIVE ARTICLE AND METHOD OF USING THE SAME 3M INNOVATIVE PROPERTIES COMPANY 2011-03-03 US disclosed