SCHEMBL837375

SCHEMBL837375

Cn1c(=O)n(CCOCCO)c(=O)n(CCOCCO)c1=O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.34
ADORA2A P29274 2/20 0.33
ADORA2B P29275 2/20 0.33
HTR1A P08908 1/20 0.33
PDE4A P27815 2/20 0.33
PDE4B Q07343 2/20 0.33
PDE4C Q08493 2/20 0.33
PDE4D Q08499 2/20 0.33
HTT P42858 2/20 0.33
MGLL Q99685 1/20 0.32
THRB P10828 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1532676 0.92 MEN1 (0.48) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL12123151 0.83 KMT2A (0.40) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL12123148 0.83 KMT2A (0.40) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL837376 0.81 MEN1 (0.45) MEN1KMT2ATSHRMAPK1HTT
SCHEMBL838042 0.81 MEN1 (0.45) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL837378 0.81 MEN1 (0.45) MEN1KMT2ATSHRMAPK1HTT
SCHEMBL2730449 0.78 PDE4A (0.41) MEN1KMT2ATSHRMAPK1ALDH1A1
SCHEMBL13413749 0.77 MEN1 (0.38) MEN1KMT2ATSHRMAPK1SMN1; SMN2
SCHEMBL13413750 0.77 MEN1 (0.38) MEN1KMT2ATSHRMAPK1SMN1; SMN2
SCHEMBL13133746 0.76 ALDH1A1 (0.44) MEN1KMT2ATSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142982-B2 Lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142978-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20090111049-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR FUJIFILM CORPORATION (JP) 2009-04-30 US disclosed
US-20080286685-A1 PLANOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed