SCHEMBL1532698

SCHEMBL1532698

OCCCCc1ccc(N2CCOCC2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC13A5 Q86YT5 1/20 0.49
MAPT P10636 5/20 0.46
GSK3B P49841 1/20 0.45
ESRRG P62508 1/20 0.45
ALDH1A1 P00352 4/20 0.45
KDM4E B2RXH2 2/20 0.45
ALOX15 P16050 2/20 0.45
HSD17B10 Q99714 2/20 0.45
HPGD P15428 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
MEN1 O00255 2/20 0.44
HTT P42858 2/20 0.44
KMT2A Q03164 2/20 0.44
CYP1A2 P05177 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
LMNA P02545 1/20 0.44
SIGMAR1 Q99720 2/20 0.44
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22558673 0.95 SLC13A5 (0.50) SLC13A5MAPTGSK3BESRRGALDH1A1
SCHEMBL931389 0.87 SLC13A5 (0.52) SLC13A5MAPTGSK3BALDH1A1KDM4E
SCHEMBL28287211 0.83 SIGMAR1 (0.60) SLC13A5MAPTALDH1A1NPC1RAB9A
SCHEMBL4969194 0.83 SLC13A5 (0.46) SLC13A5MAPTALDH1A1KDM4EALOX15
SCHEMBL19245042 0.81 S1PR1 (0.59) MAPTALDH1A1KDM4EALOX15HSD17B10
SCHEMBL22500352 0.81 MAPT (0.51) SLC13A5MAPTGSK3BALDH1A1MEN1
SCHEMBL3399680 0.81 LMNA (0.52) SLC13A5MAPTALDH1A1KDM4EALOX15
SCHEMBL10895294 0.80 SLC13A5 (0.47) SLC13A5MAPTGSK3BALDH1A1KDM4E
SCHEMBL1716021 0.80 CHKA (0.56) SLC13A5MAPTGSK3BALDH1A1KDM4E
SCHEMBL29272968 0.79 SLC13A5 (0.46) SLC13A5MAPTGSK3BALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7897304-B2 Color filter, semi-transmissive semi-reflective liquid-crystal display device, method for forming phase difference control layer, and method for manufacturing color filter DAI NIPPON PRINTING CO., LTD. (JP) 2011-03-01 US disclosed
US-20070077502-A1 Color filter, semi-transmissive semi-reflective liquid-crystal display device, method for forming phase difference control layer, and method for manufacturing color filter DAI NIPPON PRINTING CO., LTD. (JP) 2007-04-05 US disclosed
US-4853382-A TREATING ASTHMA AND BRONCHITIS GLAXO GROUP LIMITED (GB) 1989-08-01 US disclosed
EP-0178919-B1 AMINOPHENOL DERIVATIVES GLAXO GROUP LIMITED (GB) 1988-12-21 EP disclosed
US-4730008-A STIMULANT FOR BETA-ADRENORECEPTORS GLAXO GROUP LIMITED (GB) 1988-03-08 US disclosed
EP-0178919-A2 Aminophenol derivatives GLAXO GROUP LIMITED (GB) 1986-04-23 EP disclosed