Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR2 | Q9HBW0 | 19/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 16/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | TSPO | P30536 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.39 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14574775 | 0.86 | LPAR2 (0.43) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL14574774 | 0.86 | LPAR2 (0.43) | LPAR2LPAR1ADRB3TSPODRD3 | |
| SCHEMBL15327069 | 0.83 | RAB9A (0.39) | PIK3CD | |
| SCHEMBL15899984 | 0.83 | PIK3CD (0.46) | PIK3CD | |
| SCHEMBL15327098 | 0.82 | PIK3CD (0.38) | PIK3CD | |
| SCHEMBL17530792 | 0.81 | IDH1 (0.44) | PIK3CD | |
| SCHEMBL17530774 | 0.81 | IDH1 (0.46) | — | |
| SCHEMBL17530772 | 0.79 | IDH1 (0.42) | PIK3CD | |
| SCHEMBL17530767 | 0.76 | IDH1 (0.42) | — | |
| SCHEMBL17530787 | 0.73 | DPP4 (0.37) | OPRK1PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2499144-B1 | QUINOLINE AND QUINOXALINE DERIVATIVES AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2013-10-23 | — | — | EP | claimed |