Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.48 |
| ▸ | CTSL | P07711 | 13/20 | 0.48 |
| ▸ | CTSK | P43235 | 8/20 | 0.48 |
| ▸ | CTSB | P07858 | 7/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076135 | 1.00 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL15327137 | 1.00 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3064334 | 0.92 | CTSL (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL15327121 | 0.92 | CTSL (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL15327122 | 0.92 | CTSL (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3062333 | 0.91 | CTSL (0.57) | CTSSCTSLCTSKCTSB | |
| SCHEMBL2615453 | 0.91 | CTSS (0.51) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3056307 | 0.90 | CTSL (0.49) | CTSSCTSLCTSKCTSB | |
| SCHEMBL3056031 | 0.89 | CTSS (0.48) | CTSSCTSLCTSKCTSB | |
| SCHEMBL696816 | 0.88 | CTSL (0.60) | CTSSCTSLCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-B1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | disclosed |