Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 19/20 | 0.61 |
| ▸ | CTSS | P25774 | 17/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327315 | 0.97 | CTSL (0.64) | CTSLCTSSCTSK | |
| SCHEMBL15327481 | 0.95 | CTSL (0.64) | CTSLCTSSCTSK | |
| SCHEMBL15327567 | 0.94 | CTSL (0.60) | CTSLCTSSCTSK | |
| SCHEMBL15327316 | 0.94 | CTSL (0.65) | CTSLCTSSCTSK | |
| SCHEMBL15327476 | 0.93 | CTSL (0.65) | CTSLCTSSCTSK | |
| SCHEMBL15327189 | 0.91 | CTSL (0.68) | CTSLCTSSCTSK | |
| SCHEMBL15327186 | 0.91 | CTSL (0.64) | CTSLCTSSCTSK | |
| SCHEMBL15327515 | 0.91 | CTSL (0.64) | CTSLCTSSCTSK | |
| SCHEMBL15327283 | 0.91 | CTSL (0.64) | CTSLCTSSCTSK | |
| SCHEMBL15327230 | 0.90 | CTSS (0.62) | CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-B1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | claimed |