Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 16/20 | 0.62 |
| ▸ | CTSL | P07711 | 8/20 | 0.62 |
| ▸ | CTSB | P07858 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327272 | 0.91 | CTSS (0.59) | CTSSCTSLCTSB | |
| SCHEMBL15327264 | 0.90 | CTSS (0.66) | CTSSCTSLCTSB | |
| SCHEMBL15327153 | 0.88 | CTSS (0.63) | CTSSCTSLCTSB | |
| SCHEMBL693778 | 0.88 | CTSS (0.77) | CTSSCTSLCTSB | |
| SCHEMBL15327160 | 0.87 | CTSS (0.75) | CTSSCTSLCTSB | |
| SCHEMBL15327494 | 0.85 | CTSS (0.61) | CTSSCTSL | |
| SCHEMBL15327574 | 0.85 | CTSL (0.79) | CTSSCTSLCTSB | |
| SCHEMBL15327384 | 0.85 | CTSS (0.61) | CTSSCTSLCTSB | |
| SCHEMBL15327239 | 0.85 | CTSS (0.65) | CTSSCTSLCTSB | |
| SCHEMBL15327399 | 0.84 | CTSS (0.65) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421826-B1 | PROLINE DERIVATIVES AS CATHEPSIN INHIBITORS | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | claimed |