Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327582 | 0.92 | MAPK1 (0.51) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327731 | 0.91 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327633 | 0.91 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327659 | 0.91 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327674 | 0.91 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327605 | 0.90 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327601 | 0.90 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327475 | 0.90 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327627 | 0.90 | MEN1 (0.53) | ALDH1A1LMNAMAPK1KMT2AMEN1 | |
| SCHEMBL15327696 | 0.89 | LMNA (0.55) | ALDH1A1LMNAMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205573-B1 | TETRAZOLE-SUBSTITUTED ARYL AMIDE DERIVATIVES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2013-10-23 | — | — | EP | claimed |