Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7210373 | 0.98 | SLC1A3 (0.37) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL4272520 | 0.81 | ADH1B (0.34) | — | |
| SCHEMBL17416331 | 0.81 | ADH1B (0.30) | — | |
| SCHEMBL7659266 | 0.76 | SLC1A3 (0.35) | SLC1A3SLC1A2SLC1A1ALDH1A1MAPT | |
| SCHEMBL28097907 | 0.72 | PGD (0.36) | — | |
| SCHEMBL28858703 | 0.70 | ADH1B (0.30) | — | |
| SCHEMBL6289098 | 0.70 | TSHR (0.31) | — | |
| SCHEMBL1693985 | 0.69 | SLC7A5 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL8352984 | 0.69 | SLC7A5 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 | |
| SCHEMBL1770797 | 0.69 | SLC7A5 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477968-B1 | N-[2-HYDROXYCARBAMOYL-2-(PIPERAZINYL)ETHYL]BENZAMIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS TACE INHIBITORS | GALDERMA RES & DEV (FR) | 2013-10-23 | — | — | EP | disclosed |