Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5704258 | 0.82 | TSHR (0.48) | TSHRIDO1AGXTCA1CA2 | |
| SCHEMBL705851 | 0.81 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1 | |
| SCHEMBL7054298 | 0.79 | CETP (0.45) | TSHRALDH1A1 | |
| SCHEMBL6661880 | 0.77 | TSHR (0.42) | TSHRIDO1AGXTHDAC6ALDH1A1 | |
| SCHEMBL3482051 | 0.76 | TSHR (0.50) | TSHRIDO1AGXTALDH1A1LTA4H | |
| SCHEMBL11435747 | 0.73 | FOLH1 (0.39) | TSHRIDO1AGXTHDAC6HDAC3 | |
| SCHEMBL28966766 | 0.72 | TSHR (0.79) | TSHRIDO1AGXTHDAC6ALDH1A1 | |
| SCHEMBL15848468 | 0.72 | TSHR (0.45) | TSHRIDO1AGXTHDAC6ALDH1A1 | |
| SCHEMBL5682848 | 0.72 | TSHR (0.45) | TSHRIDO1AGXTALDH1A1CYP1A2 | |
| SCHEMBL10481808 | 0.71 | TSHR (0.48) | TSHRIDO1AGXTHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2393861-B1 | MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY | MOMENTIVE PERFORMANCE MAT INC (US) | 2013-10-23 | — | — | EP | claimed |