Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | S100B | P04271 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10994311 | 0.86 | MAPT (0.57) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL28157462 | 0.83 | NR4A1 (0.61) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL29350361 | 0.81 | SRD5A2 (0.74) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL522683 | 0.81 | SRD5A2 (0.74) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL4712301 | 0.80 | NR4A1 (0.68) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL3956037 | 0.80 | NR4A1 (0.68) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL460727 | 0.80 | MEN1 (0.68) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL499643 | 0.79 | SMN1; SMN2 (0.63) | ALDH1A1NR4A1SRD5A2NPSR1TP53 | |
| SCHEMBL9565886 | 0.79 | SRD5A2 (0.51) | MAPTALDH1A1LMNANR4A1SRD5A2 | |
| SCHEMBL31366555 | 0.79 | MAPT (0.61) | MAPTALDH1A1LMNANR4A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| EP-2427431-A1 | NOVEL INDICATOR PLATFORM | Biosynth AG (CH) | 2012-03-14 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |
| US-5098901-A | Cardiovascular disorders | STERLING DRUG INC. (US) | 1992-03-24 | — | — | US | disclosed |