SCHEMBL522683

SCHEMBL522683

O=C(c1ccccc1)c1ccc(Cl)cc1Cl

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.74
MAPT P10636 4/20 0.63
RAB9A P51151 3/20 0.63
SMN1; SMN2 Q16637 3/20 0.62
TSHR P16473 1/20 0.62
CASP1 P29466 1/20 0.62
TP53 P04637 1/20 0.59
CYP2C9 P11712 2/20 0.56
MEN1 O00255 1/20 0.56
POLB P06746 1/20 0.56
KMT2A Q03164 1/20 0.56
NPC1 O15118 1/20 0.56
HPGD P15428 1/20 0.56
ALDH1A1 P00352 3/20 0.55
LMNA P02545 1/20 0.55
NR4A1 P22736 1/20 0.55
HTT P42858 2/20 0.54
MITF O75030 1/20 0.54
HSP90AA1 P07900 1/20 0.54
ATM Q13315 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350361 1.00 SRD5A2 (0.74) SRD5A2MAPTRAB9ASMN1; SMN2TSHR
SCHEMBL9496067 0.88 SRD5A2 (0.79) SRD5A2MAPTRAB9ASMN1; SMN2TSHR
SCHEMBL5068843 0.87 SRD5A2 (0.68) SRD5A2MAPTRAB9ATP53POLB
SCHEMBL11851861 0.87 SRD5A2 (0.62) SRD5A2MAPTRAB9ASMN1; SMN2TSHR
SCHEMBL8437570 0.87 SRD5A2 (0.96) SRD5A2MAPTRAB9ASMN1; SMN2TSHR
SCHEMBL28157462 0.86 NR4A1 (0.61) SRD5A2MAPTRAB9ASMN1; SMN2TP53
SCHEMBL4338669 0.85 MAPT (0.68) SRD5A2MAPTRAB9ASMN1; SMN2TSHR
SCHEMBL6481029 0.85 SRD5A2 (0.65) SRD5A2MAPTRAB9ASMN1; SMN2TSHR
SCHEMBL230930 0.85 ALDH1A1 (0.63) SRD5A2MAPTRAB9ASMN1; SMN2TP53
SCHEMBL29612638 0.85 ALDH1A1 (0.63) SRD5A2MAPTRAB9ASMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2026-02-12 US claimed
EP-4680369-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GE Vernova Technology GmbH (CH) 2026-01-21 EP claimed
EP-4556112-A2 SORBENT COMPOSITIONS, SYSTEMS, AND METHODS General Electric Technology GmbH (CH) 2025-05-21 EP claimed
WO-2024232872-A1 SYSTEMS FOR CARBON DIOXIDE CAPTURE USING FUNCTIONALIZED SORBENTS AND WATER MANAGEMENT GENERAL ELECTRIC TECHNOLOGY GMBH (CH) 2024-11-14 WO claimed
US-20240199653-A1 METHOD FOR FORMING AN ELECTRICALLY CONDUCTIVE METAL ORGANIC FRAMEWORK COMPOSITE KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-06-20 US claimed
CN-116063864-A Anti-ultraviolet disperse dye, preparation method thereof and carrier dyeing process comprising anti-ultraviolet disperse dye 浙江航民股份有限公司 2023-05-05 CN claimed
CN-106929491-B (S)-carbonyl reductase heteromer and its application in the more benzene ring compounds of catalysis 江南大学 2019-09-17 CN claimed
CN-107805305-A A kind of Industrialized synthesis method of film level polyaryl ether sulphone resin 江门市优巨新材料有限公司 2018-03-16 CN claimed
CN-103613763-B A kind of high-flow polyphenylene ether sulfone ketone resin and Industrialized synthesis method thereof JIANGMEN YOUJU NEW MATERIALS Co.,Ltd. (CN) 2015-08-26 CN claimed
CN-104592515-A Industrialized synthesis method of polyether sulfone resin JIANGMEN YOUJU NEW MATERIALS CO LTD 2015-05-06 CN claimed
US-7750091-B2 Foam that is a blend of a polyphenylene with units derived from p-dichlorobenzophenone and m-dichlorobenzene and a polyphenyl ether sulfone with p,p'-biphenyl and diphenyl sulfone units; useful in numerous applications such as in the preparation of articles and of foams having reduced density SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2010-07-06 US claimed
EP-1858977-B1 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS LLC (US) 2009-06-10 EP claimed
US-20080293840-A1 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS L.L.C. (US) 2008-11-27 US claimed
EP-1858977-A2 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD Solvay Advanced Polymers, L.L.C. (US) 2007-11-28 EP claimed
WO-2006094988-A2 POLYPHENYLENE-POLY(ARYL ETHER SULFONE) BLENDS, ARTICLES AND METHOD SOLVAY ADVANCED POLYMERS, L.L.C. (US) 2006-09-14 WO claimed
EP-0480388-B1 Light-sensitive litho printing plate requiring no dampening water KONISHIROKU PHOTO IND (JP) 1998-03-18 EP claimed
US-5602228-A Nickel phosphate catalysts MAXDEM INCORPORATED (US) 1997-02-11 US claimed
WO-1996039455-A1 NICKEL PHOSPHITE CATALYSTS MAXDEM INCORPORATED (US) 1996-12-12 WO claimed
EP-0480388-A2 Light-sensitive litho printing plate requiring no dampening water KONICA CORPORATION (JP) 1992-04-15 EP claimed
US-4276369-A DECOMPOSITION BY ULTRAVIOLET RADIATION IN PRESENCE OF A BENZOPHENONE TOKYO OHKA KOGYO KABUSHIKI KAISHA (JP) 1981-06-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042084-A1 SORBENTS FUNCTIONALIZED WITH LIGANDS HAVING AN AMINOSILICONE FUNCTIONAL GROUP SRMS, TYRO3, SELE SRD5A2 3260/4885MAPT 1454/4885RAB9A 2838/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.