Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1041696 | 1.00 | MAPT (0.61) | MAPTGAAABL1POLBTDP1 | |
| SCHEMBL145366 | 0.87 | RECQL (0.67) | MAPTGAAPOLBALOX15NR4A1 | |
| SCHEMBL30484136 | 0.87 | RECQL (0.67) | MAPTGAAPOLBALOX15NR4A1 | |
| SCHEMBL31000389 | 0.87 | RECQL (0.67) | MAPTGAAPOLBALOX15NR4A1 | |
| Hydrochloric Acid SCHEMBL27581315 | 0.86 | RECQL (0.65) | MAPTGAAPOLBALOX15NR4A1 | |
| Hydrazine SCHEMBL11821861 | 0.86 | RECQL (0.65) | MAPTGAAPOLBALOX15NR4A1 | |
| SCHEMBL2241001 | 0.84 | MAPK1 (0.58) | MAPTABL1POLBTDP1ALOX15 | |
| SCHEMBL8080356 | 0.83 | AKR1C4 (0.49) | MAPTABL1TDP1ALOX15RECQL | |
| SCHEMBL28157462 | 0.83 | NR4A1 (0.61) | MAPTGAAALOX15NR4A1SRD5A2 | |
| SCHEMBL344131 | 0.83 | SMN1; SMN2 (0.51) | MAPTABL1POLBTDP1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119072467-A | Novel diazapine compounds targeting yellow fever virus non-structural 4B (NS 4B) protein and methods of use thereof | 巴鲁克斯布伦博格研究所 | 2024-12-03 | — | — | CN | disclosed |