Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18519859 | 0.63 | — | — | |
| SCHEMBL14264257 | 0.60 | — | — | |
| SCHEMBL1096504 | 0.60 | — | — | |
| SCHEMBL8312414 | 0.60 | — | — | |
| SCHEMBL7161983 | 0.57 | — | — | |
| SCHEMBL22715212 | 0.55 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1PARP1 | |
| SCHEMBL13984967 | 0.54 | — | — | |
| SCHEMBL11018441 | 0.54 | — | — | |
| SCHEMBL14216214 | 0.53 | — | — | |
| SCHEMBL1934832 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8865677-B2 | iRNA agents with biocleavable tethers | ALNYLAM PHARMACEUTICALS, INC. (US) | 2014-10-21 | — | — | US | disclosed |
| US-20130281685-A1 | iRNA AGENTS WITH BIOCLEAVABLE TETHERS | BANK OF AMERICA, N.A. | 2013-10-24 | — | — | US | disclosed |