⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13984967 | 0.72 | — | — | |
| SCHEMBL18037706 | 0.69 | — | — | |
| SCHEMBL1096504 | 0.69 | — | — | |
| SCHEMBL8312414 | 0.67 | — | — | |
| SCHEMBL11842484 | 0.67 | LMNA (0.45) | — | |
| SCHEMBL15870001 | 0.67 | ADORA1 (0.41) | — | |
| SCHEMBL21324849 | 0.67 | L3MBTL1 (0.57) | — | |
| SCHEMBL1612973 | 0.67 | — | — | |
| SCHEMBL31495235 | 0.67 | — | — | |
| SCHEMBL17671749 | 0.67 | MAPT (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120004863-A | ALK protein degradation agent and application thereof in resisting tumor | 江苏天士力帝益药业有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119528836-A | Method for synthesizing methylated azauracil derivative | 桂林理工大学 | 2025-02-28 | — | — | CN | disclosed |
| WO-2023193818-A1 | METHOD FOR SYNTHESIZING POLYSUBSTITUTED TRIAZINE COMPOUND | 湖北九康通生物医药有限公司 | 2023-10-12 | — | — | WO | disclosed |
| US-10028961-B2 | Therapeutically active compounds and their methods of use | AGIOS PHARMACEUTICALS, INC. (US) | 2018-07-24 | — | — | US | disclosed |
| US-10017495-B2 | Therapeutically active compounds and their methods of use | AGIOS PHARMACEUTICALS, INC. (US) | 2018-07-10 | — | — | US | disclosed |
| US-9751863-B2 | Therapeutically active compounds and their methods of use | AGIOS PHARMACEUTICALS, INC. (US) | 2017-09-05 | — | — | US | disclosed |
| US-20170107194-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2017-04-20 | — | — | US | disclosed |
| US-9579324-B2 | Therapeutically active compounds and their methods of use | AGIOS PHARMACEUTICALS, INC (US) | 2017-02-28 | — | — | US | disclosed |
| US-20170037031-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2017-02-09 | — | — | US | disclosed |
| US-20160237071-A1 | T-TYPE CALCIUM CHANNEL INHIBITOR | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2016-08-18 | — | — | US | disclosed |
| US-20160220572-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2016-08-04 | — | — | US | disclosed |
| US-20160220572-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2016-08-04 | — | — | US | disclosed |
| US-20160159771-A1 | THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE | SERVIER PHARMACEUTICALS LLC | 2016-06-09 | — | — | US | disclosed |
| EP-0154906-A2 | 3-Cyclopropylmethyl-1,3,5-triazine-2,4-dione | BAYER AG (DE) | 1985-09-18 | — | — | EP | disclosed |
| US-4209619-A | HEXAZINONE AND UREA | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-06-24 | — | — | US | disclosed |
| US-4174445-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-11-13 | — | — | US | disclosed |
| US-4048315-A | NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-13 | — | — | US | disclosed |