Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL138432 | 0.77 | NPSR1 (0.50) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12506409 | 0.67 | NPSR1 (0.44) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL21327987 | 0.65 | NPSR1 (0.39) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL18745271 | 0.65 | NPSR1 (0.48) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL10871242 | 0.65 | ALDH1A1 (0.39) | NPSR1ALDH1A1L3MBTL1TDP1TSHR | |
| SCHEMBL21327988 | 0.65 | NPSR1 (0.43) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL4971176 | 0.64 | ALDH1A1 (0.54) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL10653957 | 0.63 | MEN1 (0.42) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12506408 | 0.62 | MEN1 (0.33) | NPSR1ALDH1A1KMT2AMEN1HTT | |
| SCHEMBL9389957 | 0.62 | NPSR1 (0.56) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676874-B2 | Processes for preparing aminosilane functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2017-06-13 | — | — | US | claimed |
| US-20160152756-A1 | PROCESSES FOR PREPARING AMINOSILANE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2016-06-02 | — | — | US | claimed |
| US-9255158-B2 | Aminosilane initiators, functionalized polymers prepared therefrom and related processes | BRIDGESTONE CORPORATION (JP) | 2016-02-09 | — | — | US | claimed |
| US-20150099852-A1 | AMINOSILANE INITIATORS, FUNCTIONALIZED POLYMERS PREPARED THEREFROM AND RELATED PROCESSES | BRIDGESTONE CORPORATION (JP) | 2015-04-09 | — | — | US | claimed |
| US-8916665-B2 | Aminosilane initiators and functionalized polymers prepared therefrom | BRIDGESTONE CORPORATION (JP) | 2014-12-23 | — | — | US | claimed |
| EP-2658727-B1 | AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM | BRIDGESTONE CORP (JP) | 2014-12-03 | — | — | EP | claimed |
| US-20130281645-A1 | Aminosilane Initiators And Functionalized Polymers Prepared Therefrom | BRIDGESTONE CORPORATION (JP) | 2013-10-24 | — | — | US | claimed |
| US-10351636-B2 | Processes for preparing aminosilane functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2019-07-16 | — | — | US | disclosed |
| US-9676874-B2 | Processes for preparing aminosilane functionalized polymers | BRIDGESTONE CORPORATION (JP) | 2017-06-13 | — | — | US | disclosed |
| US-20160152756-A1 | PROCESSES FOR PREPARING AMINOSILANE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORPORATION (JP) | 2016-06-02 | — | — | US | disclosed |
| US-9255158-B2 | Aminosilane initiators, functionalized polymers prepared therefrom and related processes | BRIDGESTONE CORPORATION (JP) | 2016-02-09 | — | — | US | disclosed |
| US-20150099852-A1 | AMINOSILANE INITIATORS, FUNCTIONALIZED POLYMERS PREPARED THEREFROM AND RELATED PROCESSES | BRIDGESTONE CORPORATION (JP) | 2015-04-09 | — | — | US | disclosed |
| US-8916665-B2 | Aminosilane initiators and functionalized polymers prepared therefrom | BRIDGESTONE CORPORATION (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2658727-B1 | AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM | BRIDGESTONE CORP (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20130281645-A1 | Aminosilane Initiators And Functionalized Polymers Prepared Therefrom | BRIDGESTONE CORPORATION (JP) | 2013-10-24 | — | — | US | disclosed |