Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073528 | 0.73 | NPSR1 (0.50) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL28645851 | 0.69 | NPSR1 (0.50) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL9743840 | 0.69 | ALDH1A1 (0.58) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12506391 | 0.68 | NPSR1 (0.44) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL21327987 | 0.67 | NPSR1 (0.39) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL988299 | 0.67 | ALDH1A1 (0.54) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL15328666 | 0.67 | NPSR1 (0.43) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL195179 | 0.67 | NPSR1 (0.54) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL11252920 | 0.67 | ALDH1A1 (0.50) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL12699618 | 0.65 | NPSR1 (0.46) | NPSR1ALDH1A1KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2658727-A1 | AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM | Bridgestone Corporation (JP) | 2013-11-06 | — | — | EP | claimed |
| WO-2012091753-A1 | AMINOSILANE INITIATORS AND FUNCTIONALIZED POLYMERS PREPARED THEREFROM | BRIDGESTONE CORPORATION (JP) | 2012-07-05 | — | — | WO | claimed |