Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.64 |
| ▸ | FPR1 | P21462 | 1/20 | 0.64 |
| ▸ | GPR183 | P32249 | 1/20 | 0.64 |
| ▸ | APLNR | P35414 | 1/20 | 0.64 |
| ▸ | GLP1R | P43220 | 1/20 | 0.64 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.64 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.64 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | FABP4 | P15090 | 7/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP9 | P55211 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1834798 | 0.89 | ADRB2 (0.67) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1833669 | 0.87 | GPBAR1 (0.79) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1832908 | 0.86 | GPBAR1 (0.72) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1835619 | 0.85 | ADRB2 (0.71) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1833921 | 0.84 | ADRB2 (0.75) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1835545 | 0.84 | GPBAR1 (0.71) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1836114 | 0.82 | ADRB2 (0.68) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1833517 | 0.82 | GPBAR1 (0.70) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1845636 | 0.81 | ADRB2 (0.64) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL1839885 | 0.81 | ADRB2 (0.75) | ADRB2FPR1GPR183APLNRGLP1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130281435-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | TAKEDA PHARMACEUTICAL COMPANY LIMITED | 2013-10-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281435-A1 | THERAPEUTIC AGENT FOR IRRITABLE BOWEL SYNDROME | GPBAR1, GPR35, GRPR | ADRB2 187/4885FPR1 426/4885GPR183 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.