Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19282553 | 0.83 | HCAR2 (0.46) | KDM4EALDH1A1MEN1KMT2AHCAR2 | |
| SCHEMBL1025623 | 0.81 | POLB (0.44) | KDM4EALDH1A1MEN1KMT2APOLB | |
| SCHEMBL20608764 | 0.81 | HCAR2 (0.44) | KDM4EALDH1A1MEN1KMT2AHCAR2 | |
| SCHEMBL3576453 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2AHCAR2 | |
| SCHEMBL23854652 | 0.79 | KDM4E (0.36) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL22289328 | 0.78 | HCAR2 (0.40) | KDM4EALDH1A1MEN1KMT2AHCAR2 | |
| SCHEMBL1024857 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL14910266 | 0.75 | KDM4E (0.33) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL1024856 | 0.74 | GRM5 (0.34) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL1555330 | 0.74 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919494-B2 | Pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound | ASTELLAS PHARMA, INC. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7919495-B2 | Pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound | ASTELLAS PHARMA, INC. (JP) | 2011-04-05 | — | — | US | disclosed |
| US-7915261-B2 | Pyridyl non-aromatic nitrogen-containing heterocyclic-1-carboxylate compound | ASTELLAS PHARMA, INC. (JP) | 2011-03-29 | — | — | US | disclosed |