SCHEMBL15329316

SCHEMBL15329316

COC(OC)[SiH2]CCc1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
CYP2A6 P11509 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
MAPT P10636 1/20 0.38
AGXT P21549 2/20 0.36
IDO1 P14902 1/20 0.35
KCNH2 Q12809 3/20 0.35
HRH3 Q9Y5N1 1/20 0.35
IGF1R P08069 1/20 0.34
ALOX15 P16050 1/20 0.34
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CHKA P35790 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163506 0.92 TAAR1 (0.34) TAAR1
SCHEMBL8961186 0.83 LOXL2 (0.38) TAAR1HRH3
SCHEMBL2244720 0.79 IDO1 (0.30) IDO1
SCHEMBL2246130 0.77 TAAR1 (0.38) TAAR1HRH3MEN1KMT2A
SCHEMBL446129 0.76 CYP1A2 (0.45) CYP1A2CYP2A6TAAR1MAPTAGXT
SCHEMBL31070320 0.72 IDO1 (0.41) IDO1KCNH2L3MBTL1MEN1KMT2A
SCHEMBL10612702 0.70 MAOB (0.49) TAAR1MAPTALDH1A1LMNA
SCHEMBL15329315 0.70 TAAR1 (0.46) TAAR1MAPTLMNAMEN1KMT2A
SCHEMBL31299572 0.70 CYP1A2 (0.52) CYP1A2CYP2A6TAAR1MAPTAGXT
SCHEMBL143961 0.68 CYP1A2 (0.68) CYP1A2CYP2A6TAAR1AGXTIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8967178-B2 Saturation valve assembly for electric cables UTILX CORPORATION (US) 2015-03-03 US claimed
US-20130276907-A1 VALVE ASSEMBLY UTILX CORPORATION (US) 2013-10-24 US claimed
US-8967178-B2 Saturation valve assembly for electric cables UTILX CORPORATION (US) 2015-03-03 US disclosed
US-20130276907-A1 VALVE ASSEMBLY UTILX CORPORATION (US) 2013-10-24 US disclosed