SCHEMBL446129

SCHEMBL446129

Cc1ccc(CC[SiH2]C(Cl)Cl)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.45
CYP2A6 P11509 1/20 0.45
TAAR1 Q96RJ0 1/20 0.45
IDO1 P14902 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
KCNH2 Q12809 1/20 0.37
IGF1R P08069 1/20 0.36
ALOX15 P16050 1/20 0.36
AGXT P21549 2/20 0.34
TP53 P04637 1/20 0.34
MAPT P10636 1/20 0.34
CHKA P35790 1/20 0.34
TDP1 Q9NUW8 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HRH1 P35367 1/20 0.33
FFAR1 O14842 1/20 0.33
ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7534974 0.83 L3MBTL1 (0.45) CYP2A6TAAR1ALDH1A1TP53TDP1
SCHEMBL4929092 0.81 CA1 (0.33)
SCHEMBL448811 0.78 ALDH1A1 (0.42) CYP1A2CYP2A6TAAR1IDO1ALDH1A1
SCHEMBL15329316 0.76 CYP1A2 (0.42) CYP1A2CYP2A6TAAR1IDO1ALDH1A1
SCHEMBL7975652 0.75 ALDH1A1 (0.41) ALDH1A1
SCHEMBL31299572 0.73 CYP1A2 (0.52) CYP1A2CYP2A6TAAR1IDO1ALDH1A1
SCHEMBL8859947 0.72 KMT2A (0.40) CYP1A2CYP2A6TAAR1ALDH1A1MEN1
SCHEMBL10707889 0.71 CYP1A2 (0.50) CYP1A2CYP2A6TAAR1IDO1ALDH1A1
SCHEMBL11288839 0.71 CYP1A2 (0.68) CYP1A2CYP2A6TAAR1IDO1ALDH1A1
SCHEMBL143961 0.71 CYP1A2 (0.68) CYP1A2CYP2A6TAAR1IDO1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060110351-A1 Use of silanes on cosmetic agents and methods for treating hair ITN NANOVATION AG (DE) 2006-05-25 US claimed
EP-1555990-A1 USE OF SILANES IN COSMETIC AGENTS AND METHODS FOR TREATING HAIR ITN NANOVATION GMBH (DE) 2005-07-27 EP claimed
WO-2004012691-A1 USE OF SILANES IN COSMETIC AGENTS AND METHODS FOR TREATING HAIR ITN NANOVATION GMBH (DE) 2004-02-12 WO claimed
EP-0853482-A4 WATER-STABILIZED ORGANOSILANES AND METHODS FOR USE UNIV EMORY (US) 2002-07-31 EP claimed
US-6221944-B1 SURFACE TREATMENT EMORY UNIVERSITY 2001-04-24 US claimed
US-6113815-A HYDROLYSIS RESISTANCE BIOSHIELD TECHNOLOGIES, INC. (US) 2000-09-05 US claimed
EP-0996624-A1 WATER-STABILIZED ORGANOSILANE COMPOUNDS AND METHODS FOR USING THE SAME Bioshield Technologies, Inc. (US) 2000-05-03 EP claimed
US-5959014-A A REACTION PRODUCT OF AN ORGANOSILANE COMPOUND AND A POLYOL COMPOUND FOR TREATING VARIOUS SUBSTRATES; NON-TOXIC, NON-FLAMMABLE, SIMPLE, ECONOMICAL AND ARE OPERABLE OVER A WIDE VARIETY OF PH RANGES; ANTIMICROBIAL PROTECTIVE COATINGS EMORY UNIVERSITY (US) 1999-09-28 US claimed
WO-1999003865-A1 WATER-STABILIZED ORGANOSILANE COMPOUNDS AND METHODS FOR USING THE SAME BIOSHIELD TECHNOLOGIES, INC. (US) 1999-01-28 WO claimed
EP-0877027-A2 Water-stabilized organosilane compounds and methods for using the same Bioshield Technologies, Inc. (US) 1998-11-11 EP claimed
EP-0853482-A1 WATER-STABILIZED ORGANOSILANES AND METHODS FOR USE EMORY UNIVERSITY (US) 1998-07-22 EP claimed
WO-1997041876-A1 WATER-STABILIZED ORGANOSILANES AND METHODS FOR USE EMORY UNIVERSITY (US) 1997-11-13 WO claimed
US-20220016292-A1 Antiviral Compound with UV Reflectivity DE NOVA TECHNOLOGY INC. 2022-01-20 US disclosed
US-9175141-B2 Cyclosiloxane-substituted polysiloxane compounds, compositions containing the compounds and methods of use thereof BIOFILM IP, LLC (US) 2015-11-03 US disclosed
US-8999363-B2 Methods and compositions for antimicrobial surfaces SISHIELD TECHNOLOGIES, INC. (US) 2015-04-07 US disclosed
US-8999357-B2 Methods and compositions for biocidal treatments SISHIELD TECHNOLOGIES, INC. (US) 2015-04-07 US disclosed
EP-0877027-A2 Water-stabilized organosilane compounds and methods for using the same Bioshield Technologies, Inc. (US) 1998-11-11 EP disclosed
EP-0853482-A1 WATER-STABILIZED ORGANOSILANES AND METHODS FOR USE EMORY UNIVERSITY (US) 1998-07-22 EP disclosed
WO-1997041876-A1 WATER-STABILIZED ORGANOSILANES AND METHODS FOR USE EMORY UNIVERSITY (US) 1997-11-13 WO disclosed
WO-1997041729-A1 METHODS FOR USING WATER-STABILIZED ORGANOSILANES EMORY UNIVERSITY (US) 1997-11-13 WO disclosed