Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555039 | 0.95 | KDM4E (0.60) | KDM4ETSHRTP53ALDH1A1HTT | |
| SCHEMBL29951665 | 0.88 | LTA4H (0.61) | KDM4ETSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29957497 | 0.87 | BACE1 (0.62) | KDM4ETSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL29957034 | 0.87 | BACE1 (0.62) | KDM4ETSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL2555773 | 0.85 | NPC1 (0.56) | KDM4ETSHRALDH1A1SMN1; SMN2LTA4H | |
| SCHEMBL2821196 | 0.82 | KDM4E (0.62) | KDM4ETSHRALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL24862351 | 0.81 | KDM4E (0.65) | KDM4ETSHRTP53ALDH1A1HTT | |
| SCHEMBL2557377 | 0.81 | KMT2A (0.63) | KDM4EALDH1A1HTTSMN1; SMN2LTA4H | |
| SCHEMBL2558114 | 0.81 | LTA4H (0.49) | KDM4ETSHRALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL14578276 | 0.80 | ALDH1A1 (0.69) | KDM4ETSHRTP53ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |