Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | DGAT2 | Q96PD7 | 9/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2556054 | 0.91 | MAPK13 (0.44) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2557720 | 0.90 | TP53 (0.40) | ESR1TP53KCNN4 | |
| SCHEMBL15329947 | 0.88 | KCNN4 (0.44) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2555658 | 0.86 | P2RX7 (0.37) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2560310 | 0.86 | MAPK13 (0.41) | MAPK13MAPK12MAPK11MAPK14KMT2A | |
| SCHEMBL2558574 | 0.86 | MAPK11 (0.39) | MAPK13MAPK12MAPK11MAPK14TP53 | |
| SCHEMBL15332298 | 0.86 | ESR1 (0.40) | ESR1RIPK1TP53IDO1TDO2 | |
| SCHEMBL2553216 | 0.85 | ESR1 (0.37) | ESR1RIPK1TP53KCNN4 | |
| SCHEMBL15331283 | 0.84 | ESR1 (0.42) | MAPK13MAPK12MAPK11MAPK14ESR1 | |
| SCHEMBL2559073 | 0.84 | MAPK14 (0.45) | MAPK13MAPK12MAPK11MAPK14TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |