Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329813 | 0.90 | KCNN4 (0.44) | KCNN4MAPTMAPK11MAPK14KMT2A | |
| SCHEMBL29957276 | 0.90 | MAPK14 (0.37) | KCNN4MAPK11MAPK14HPGDKMT2A | |
| SCHEMBL29951228 | 0.90 | KCNN4 (0.42) | KCNN4HPGDKMT2A | |
| SCHEMBL2555658 | 0.88 | P2RX7 (0.37) | KCNN4MAPTMAPK11MAPK14HPGD | |
| SCHEMBL2560310 | 0.88 | MAPK13 (0.41) | KCNN4MAPK11MAPK14KMT2AMAPK13 | |
| SCHEMBL15329609 | 0.88 | MAPK13 (0.40) | KCNN4MAPK11MAPK14KMT2AMAPK13 | |
| SCHEMBL2556054 | 0.88 | MAPK13 (0.44) | KCNN4MAPK11MAPK14KMT2AMAPK13 | |
| SCHEMBL15330388 | 0.87 | KCNN4 (0.46) | KCNN4MAPTMAPK11MAPK14HPGD | |
| SCHEMBL15330181 | 0.87 | MAPK14 (0.40) | KCNN4MAPTMAPK11MAPK14KMT2A | |
| SCHEMBL2559753 | 0.86 | RIPK1 (0.36) | KCNN4MAPTMAPK11MAPK14HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |