Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 1/20 | 0.67 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555989 | 0.91 | LIPE (0.69) | LIPEENPP2IDO1S1PR5FFAR1 | |
| SCHEMBL18171929 | 0.85 | LIPE (0.63) | LIPEENPP2LMNA | |
| SCHEMBL18171926 | 0.85 | LIPE (0.63) | LIPEENPP2LMNA | |
| SCHEMBL2574767 | 0.82 | LIPE (0.71) | LIPEENPP2HRH3 | |
| SCHEMBL132403 | 0.80 | LIPE (1.00) | LIPEENPP2LMNA | |
| SCHEMBL1660589 | 0.80 | LIPE (0.58) | LIPEENPP2LMNA | |
| SCHEMBL29952115 | 0.80 | LIPE (0.58) | LIPEENPP2LMNA | |
| SCHEMBL29591898 | 0.80 | LIPE (1.00) | LIPEENPP2LMNA | |
| SCHEMBL2560073 | 0.79 | LIPE (0.53) | LIPEENPP2IDO1 | |
| SCHEMBL2556728 | 0.79 | LIPE (0.61) | LIPEENPP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |