Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 10/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555989 | 0.87 | LIPE (0.69) | LIPECYP11B1CYP11B2ENPP2IDO1 | |
| SCHEMBL29958205 | 0.84 | LIPE (0.75) | LIPELTA4HENPP2ABCB1IDO1 | |
| SCHEMBL2553447 | 0.82 | CYP11B1 (0.52) | CYP11B1CYP11B2LTA4HCYP19A1PIM1 | |
| SCHEMBL2557329 | 0.81 | PIM1 (0.40) | CYP11B1CYP11B2LTA4HCYP19A1TNF | |
| SCHEMBL15329653 | 0.79 | LIPE (0.67) | LIPEENPP2IDO1 | |
| SCHEMBL2559650 | 0.78 | LIPE (0.49) | LIPEENPP2ABCB1 | |
| SCHEMBL18171929 | 0.77 | LIPE (0.63) | LIPEENPP2 | |
| SCHEMBL18171926 | 0.77 | LIPE (0.63) | LIPEENPP2 | |
| SCHEMBL7832219 | 0.76 | CYP11B1 (0.55) | CYP11B1CYP11B2LTA4HABCB1IDO1 | |
| SCHEMBL1684575 | 0.74 | LIPE (0.59) | LIPEENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |