Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 16/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | NCF1 | P14598 | 1/20 | 0.55 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954738 | 0.87 | ALDH1A1 (0.68) | ALDH1A1HTTKDM4E | |
| SCHEMBL2556300 | 0.82 | ALDH1A1 (0.51) | ALDH1A1HTTKDM4E | |
| SCHEMBL20680172 | 0.82 | CHKA (0.57) | CHKACA2NCF1PRMT6ALDH1A1 | |
| SCHEMBL16121611 | 0.80 | CHKA (0.69) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL15331774 | 0.80 | ALDH1A1 (0.50) | NCF1ALDH1A1HTT | |
| SCHEMBL31082092 | 0.79 | ALDH1A1 (0.60) | CHKANCF1ALDH1A1HTTKDM4E | |
| SCHEMBL12891510 | 0.79 | ALDH1A1 (0.69) | CHKACA2NCF1PRMT6ALDH1A1 | |
| SCHEMBL20605142 | 0.78 | HRH3 (0.51) | NCF1ALDH1A1HTT | |
| SCHEMBL14612427 | 0.77 | CHKA (0.75) | CHKACA2NCF1PRMT6KDM4E | |
| SCHEMBL2561782 | 0.77 | ALDH1A1 (0.46) | ALDH1A1HTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |