Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329682 | 0.87 | CHKA (0.62) | ALDH1A1HTTKDM4E | |
| SCHEMBL2556300 | 0.86 | ALDH1A1 (0.51) | ALDH1A1HTTSMN1; SMN2KDM4EPOLB | |
| SCHEMBL15331774 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HTTSMN1; SMN2HRH3 | |
| SCHEMBL19211682 | 0.85 | ALDH1A1 (0.65) | ALDH1A1HTTSMN1; SMN2HRH3KDM4E | |
| SCHEMBL20605142 | 0.84 | HRH3 (0.51) | ALDH1A1HTTSMN1; SMN2HRH3 | |
| SCHEMBL2561782 | 0.83 | ALDH1A1 (0.46) | ALDH1A1HTTSMN1; SMN2KDM4ECYP2D6 | |
| SCHEMBL31082092 | 0.82 | ALDH1A1 (0.60) | ALDH1A1HTTSMN1; SMN2HRH3KDM4E | |
| SCHEMBL13293320 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HTTSMN1; SMN2HRH3KDM4E | |
| SCHEMBL2553727 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTTKDM4E | |
| SCHEMBL24746120 | 0.80 | ALDH1A1 (0.72) | ALDH1A1HTTSMN1; SMN2HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |