Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.30 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331474 | 0.88 | CASP6 (0.43) | CASP6HCRTR1HCRTR2CYP3A4MAPK9 | |
| SCHEMBL28407536 | 0.80 | CASP6 (0.56) | CASP6MAPK9MAPK10KMO | |
| SCHEMBL29542837 | 0.78 | CASP6 (0.45) | CASP6MAPK9MAPK10KMO | |
| SCHEMBL24799564 | 0.78 | CASP6 (0.45) | CASP6MAPK9MAPK10KMO | |
| SCHEMBL21352408 | 0.77 | CASP6 (0.36) | CASP6 | |
| SCHEMBL493200 | 0.76 | CASP6 (0.43) | CASP6HCRTR1HCRTR2 | |
| SCHEMBL2550962 | 0.75 | ENPP2 (0.38) | CASP6MAPK9MAPK10KMO | |
| SCHEMBL15330562 | 0.72 | ENPP2 (0.38) | CASP6HCRTR1HCRTR2KMO | |
| SCHEMBL15330200 | 0.72 | KAT6A (0.39) | HCRTR1HCRTR2CYP3A4KMO | |
| SCHEMBL15332626 | 0.72 | KAT6A (0.39) | HCRTR1HCRTR2CYP3A4KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |