Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2838581 | 0.81 | ERN1 (0.69) | ERN1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL2555908 | 0.79 | ERN1 (0.54) | ERN1ALDH1A1KDM4EKMT2AGAA | |
| SCHEMBL29953284 | 0.79 | ERN1 (0.59) | ERN1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL15332076 | 0.78 | ERN1 (0.50) | ERN1ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL2559632 | 0.78 | TUBB4A (0.45) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL27773237 | 0.77 | ERN1 (0.64) | ERN1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL2557779 | 0.76 | ALDH1A1 (0.69) | ERN1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL766081 | 0.74 | ERN1 (1.00) | ERN1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL29672629 | 0.74 | ERN1 (1.00) | ERN1ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL2559846 | 0.74 | KMT2A (0.50) | ALDH1A1KDM4EHSD17B10KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |