Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 9/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557695 | 0.88 | KMT2A (0.54) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL15331675 | 0.83 | PTGS2 (0.41) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL2551858 | 0.82 | PTGS2 (0.40) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL4917849 | 0.78 | KMT2A (0.70) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL15333086 | 0.77 | LMNA (0.38) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3447906 | 0.76 | PTGS2 (1.00) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL23392558 | 0.76 | PTGS2 (0.86) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL15331394 | 0.75 | PTGS2 (0.35) | PTGS2SMN1; SMN2POLBRAB9APKM | |
| SCHEMBL15331523 | 0.74 | PTGS2 (0.34) | PTGS2POLBRAB9APKMLMNA | |
| SCHEMBL15330207 | 0.74 | LMNA (0.41) | PTGS2KMT2AALDH1A1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |