Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 5/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4286132 | 0.92 | PLA2G1B (0.46) | DNM1PLA2G1BPLA2G2AKCNH2 | |
| SCHEMBL9163925 | 0.75 | DNM1 (0.52) | DNM1PLA2G1BPLA2G2AGGPS1TSHR | |
| SCHEMBL10712988 | 0.75 | DNM1 (0.52) | DNM1PLA2G1BPLA2G2AGGPS1TSHR | |
| SCHEMBL10411256 | 0.75 | DNM1 (0.52) | DNM1PLA2G1BPLA2G2AGGPS1TSHR | |
| SCHEMBL25278830 | 0.73 | DNM1 (0.44) | DNM1PLA2G1BPLA2G2AGGPS1TSHR | |
| SCHEMBL4448024 | 0.73 | DNM1 (0.44) | DNM1PLA2G1BPLA2G2AGGPS1TSHR | |
| SCHEMBL22354437 | 0.73 | PLA2G1B (0.47) | DNM1PLA2G1BPLA2G2AGGPS1TSHR | |
| SCHEMBL25240070 | 0.73 | DNM1 (0.44) | DNM1PLA2G1BPLA2G2AGGPS1TSHR | |
| SCHEMBL24187667 | 0.72 | DNM1 (0.61) | DNM1PLA2G1BPLA2G2ATSHRTHRB | |
| SCHEMBL11791423 | 0.72 | DNM1 (0.61) | DNM1PLA2G1BPLA2G2ATSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2293670-B1 | COMPOSITIONS AND METHODS FOR NAIL FUNGUS TREATMENT | ARCH CHEM INC (US) | 2016-03-30 | — | — | EP | disclosed |
| EP-2293670-A1 | COMPOSITIONS AND METHODS FOR NAIL FUNGUS TREATMENT | Arch Chemicals, Inc. (US) | 2011-03-16 | — | — | EP | disclosed |
| WO-2009148794-A1 | COMPOSITIONS AND METHODS FOR NAIL FUNGUS TREATMENT | ARCH CHEMICALS, INC. (US) | 2009-12-10 | — | — | WO | disclosed |
| US-20090298805-A1 | TOPICAL PYRITHIONE COMPOSITIONS AND METHODS FOR TREATMENT OF NAIL FUNGUS | ARCH CHEMICALS, INC. | 2009-12-03 | — | — | US | disclosed |