Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 11/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532983 | 0.92 | DNM1 (0.41) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL20076415 | 0.77 | PLA2G1B (0.50) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL23846697 | 0.77 | PLA2G1B (0.50) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL15384677 | 0.77 | PLA2G1B (0.50) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL9350349 | 0.75 | PLA2G1B (0.48) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL3414531 | 0.75 | DNM1 (0.55) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL11336824 | 0.75 | KCNH2 (0.57) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL9852686 | 0.75 | KCNH2 (0.57) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL613374 | 0.75 | DNM1 (0.55) | PLA2G1BPLA2G2AKCNH2DNM1 | |
| SCHEMBL516346 | 0.75 | KCNH2 (0.57) | PLA2G1BPLA2G2AKCNH2DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575617-A1 | USE OF TOPICAL PHARMACEUTICAL COMPOSITIONS COMPRISING AN ACTIVE AGENT AND PERMEATION-ENHANCING BASE FOR THE MANUFACTURE OF A MEDICAMENT TO TREAT VARIOUS FORMS OF INFLAMMATORY DERMATOSIS | Dermatrends, Inc. (US) | 2005-09-21 | — | — | EP | claimed |
| EP-1558228-A1 | TOPICAL ADMINISTRATION OF BASIC ANTIFUNGAL COMPOSITIONS TO TREAT FUNGAL INFECTIONS OF THE NAILS | Dermatrends, Inc. (US) | 2005-08-03 | — | — | EP | claimed |
| EP-1556008-A1 | USE OF BASES FOR THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF DIFFERENT FORMS OF INFLAMMATORY DERMATOSIS | Dermatrends, Inc. (US) | 2005-07-27 | — | — | EP | claimed |
| EP-1429791-A4 | METHOD AND TOPICAL FORMULATION FOR TREATING SKIN CONDITIONS ASSOCIATED WITH AGING | DERMATRENDS INC (US) | 2005-01-05 | — | — | EP | claimed |
| US-6821523-B2 | APPLYING BASIC DRUGS TO SKINS FOR PROPHYLAXIS OF HUMAN PAPILLOMAVIRUS INFECTIONS; SKIN DISODERS | DERMATRENDS, INC. | 2004-11-23 | — | — | US | claimed |
| EP-1429791-A2 | METHOD AND TOPICAL FORMULATION FOR TREATING SKIN CONDITIONS ASSOCIATED WITH AGING | Dermatrends, Inc. (US) | 2004-06-23 | — | — | EP | claimed |
| WO-2004000360-A1 | USE OF TOPICAL PHARMACEUTICAL COMPOSITIONS COMPRISING AN ACTIVE AGENT AND PERMEATION-ENHANCING BASE FOR THE MANUFACTURE OF A MEDICAMENT TO TREAT VARIOUS FORMS OF INFLAMMATORY DERMATOSIS | DERMATRENDS, INC. (US) | 2003-12-31 | — | — | WO | claimed |
| WO-2004000259-A1 | TOPICAL ADMINISTRATION OF PHARMACOLOGICALLY ACTIVE BASES FOR SKIN LIGHTENING | DERMATRENDS, INC. (US) | 2003-12-31 | — | — | WO | claimed |
| WO-2004000359-A1 | TOPICAL PHARMACEUTICAL COMPOSITION COMPRISING SKIN PENETRATION ENHANCERS FOR THE TREATMENT OF WARTS | DERMATRENDS, INC. (US) | 2003-12-31 | — | — | WO | claimed |
| WO-2004000291-A1 | TOPICAL ADMINISTRATION OF BASIC ANTIFUNGAL COMPOSITIONS TO TREAT FUNGAL INFECTIONS OF THE NAILS | DERMATRENDS, INC. (US) | 2003-12-31 | — | — | WO | claimed |
| US-20030235543-A1 | Topical administration of pharmacologically active bases for skin lightening | MAIBACH HOWARD I (US) | 2003-12-25 | — | — | US | claimed |
| US-20030235627-A1 | Topical administration of pharmacologically active bases in the treatment of warts | TECHNOLOGY RECOVERY SYSTEMS, LLC | 2003-12-25 | — | — | US | claimed |
| US-20030235626-A1 | Topical administration of pharmacologically active bases in the treatment of inflammatory dermatoses | TECHNOLOGY RECOVERY SYSTEMS, LLC | 2003-12-25 | — | — | US | claimed |
| US-20030235541-A1 | Topical administration of basic antifungal compositions to treat fungal infections of the nails | TECHNOLOGY RECOVERY SYSTEMS, LLC | 2003-12-25 | — | — | US | claimed |
| US-20030099678-A1 | Method and topical formulation for treating skin conditions associated with aging | TECHNOLOGY RECOVERY SYSTEMS, LLC | 2003-05-29 | — | — | US | claimed |
| US-20030077301-A1 | Topical pharmaceutical composition for the treatment of inflammatory dermatoses | DERMATRENDS, INC. | 2003-04-24 | — | — | US | claimed |
| US-20030072814-A1 | Topical pharmaceutical composition for the treatment of warts | DERMATRENDS, INC. | 2003-04-17 | — | — | US | claimed |
| US-20030072724-A1 | Topical pharmaceutical composition to treat hyperpigmentation of the skin | MAIBACH HOWARD I (US) | 2003-04-17 | — | — | US | claimed |
| WO-2003026680-A2 | METHOD AND TOPICAL FORMULATION FOR TREATING SKIN CONDITIONS ASSOCIATED WITH AGING | DERMATRENDS, INC. (US) | 2003-04-03 | — | — | WO | claimed |
| US-20030059450-A1 | Method and topical formulation for treating skin conditions associated with aging | MAIBACH HOWARD I (US) | 2003-03-27 | — | — | US | claimed |